TY  - JOUR
AU  - Paoletti, Daniele
AU  - Caucci, Martina
AU  - Muscariello, Carmine
AU  - Esposito, Rosa
AU  - Cavarra, Francesco
AU  - Lorusso, Mauro
AU  - Ciavarella, Domenico
AU  - Tepedino, Michele
PY  - 2026
DA  - 2026/09/18
TI  - Effect of Silver Nanoparticle Incorporation into an Epoxy Resin-Based Endodontic Sealer on Dentinal Tubule Penetration: An In Vitro Scanning Electron Microscopy Study
JO  - Journal of Oral and Dental Approaches
T2  - Journal of Oral and Dental Approaches
JF  - Journal of Oral and Dental Approaches
VL  - 1
IS  - 1
SP  - 4
EP  - 12
DO  - 10.62762/JODA.2026.359949
UR  - https://www.icck.org/article/abs/JODA.2026.359949
KW  - silver nanoparticles
KW  - endodontic sealer
KW  - dentinal tubule penetration
KW  - epoxy resin-based sealer
KW  - root canal obturation
KW  - scanning electron microscopy
KW  - endodontics
KW  - nanotechnology
AB  - The long-term success of root canal treatment relies on effective chemomechanical disinfection and the ability of endodontic sealers to penetrate dentinal tubules, thereby improving the seal and limiting residual bacterial colonization. Silver nanoparticles (AgNPs) have attracted attention for their broad-spectrum antimicrobial activity; however, their influence on the dentinal tubule penetration of epoxy resin-based sealers remains incompletely understood. This study aimed to evaluate the effect of incorporating silver nanoparticles into an epoxy resin-based endodontic sealer on dentinal tubule penetration using scanning electron microscopy (SEM). Extracted human single-rooted teeth were instrumented, irrigated, and randomly allocated into a control group obturated with a conventional epoxy resin-based sealer and an experimental group obturated with the same sealer modified with silver nanoparticles. After setting, specimens were longitudinally sectioned and examined by SEM. The experimental sealer showed satisfactory adaptation and effective penetration comparable to the control group. Incorporating silver nanoparticles appears to preserve dentinal tubule penetration while potentially providing additional antimicrobial advantages, suggesting that modified sealers represent a promising strategy for enhancing endodontic disinfection without compromising sealing performance.
SN  - pending
PB  - Institute of Central Computation and Knowledge
LA  - English
ER  - 

@article{Paoletti2026Effect,
  author = {Daniele Paoletti and Martina Caucci and Carmine Muscariello and Rosa Esposito and Francesco Cavarra and Mauro Lorusso and Domenico Ciavarella and Michele Tepedino},
  title = {Effect of Silver Nanoparticle Incorporation into an Epoxy Resin-Based Endodontic Sealer on Dentinal Tubule Penetration: An In Vitro Scanning Electron Microscopy Study},
  journal = {Journal of Oral and Dental Approaches},
  year = {2026},
  volume = {1},
  number = {1},
  pages = {4-12},
  doi = {10.62762/JODA.2026.359949},
  url = {https://www.icck.org/article/abs/JODA.2026.359949},
  abstract = {The long-term success of root canal treatment relies on effective chemomechanical disinfection and the ability of endodontic sealers to penetrate dentinal tubules, thereby improving the seal and limiting residual bacterial colonization. Silver nanoparticles (AgNPs) have attracted attention for their broad-spectrum antimicrobial activity; however, their influence on the dentinal tubule penetration of epoxy resin-based sealers remains incompletely understood. This study aimed to evaluate the effect of incorporating silver nanoparticles into an epoxy resin-based endodontic sealer on dentinal tubule penetration using scanning electron microscopy (SEM). Extracted human single-rooted teeth were instrumented, irrigated, and randomly allocated into a control group obturated with a conventional epoxy resin-based sealer and an experimental group obturated with the same sealer modified with silver nanoparticles. After setting, specimens were longitudinally sectioned and examined by SEM. The experimental sealer showed satisfactory adaptation and effective penetration comparable to the control group. Incorporating silver nanoparticles appears to preserve dentinal tubule penetration while potentially providing additional antimicrobial advantages, suggesting that modified sealers represent a promising strategy for enhancing endodontic disinfection without compromising sealing performance.},
  keywords = {silver nanoparticles, endodontic sealer, dentinal tubule penetration, epoxy resin-based sealer, root canal obturation, scanning electron microscopy, endodontics, nanotechnology},
  issn = {pending},
  publisher = {Institute of Central Computation and Knowledge}
}