ICCK

xiaoli li

University of Macau, Macao

Section 01

Academic Profile

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Section 02

Editorial Roles

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Section 03

ICCK Publications

Open Access | Research Article | 13 July 2026
Cross-Frequency Graph-Transformer Networks for Subject-Independent EEG Classification of Neurodegenerative Disorders
Journal of Artificial Intelligence in Bioinformatics | Volume 2, Issue 2: 22-30, 2026 | DOI: 10.62762/JAIB.2026.815471
Abstract
Resting-state EEG offers a low-cost, non-invasive biomarker for Alzheimer's and Parkinson's diseases, yet most deep learning models fail to generalize to new patients due to subject-dependent evaluation protocols, isolated frequency-band processing, and the neglect of cross-frequency interactions. We propose CFGT-Net, a Cross-Frequency Graph-Transformer Network. For each EEG epoch, five canonical bands are processed by a graph attention encoder on a learnable phase-lag index adjacency to produce spatial embeddings. A cross-frequency coupling (CFC) attention models band interactions, a temporal transformer tracks their evolution across epochs, and a correlation-alignment loss enforces subject... More >

Graphical Abstract
Cross-Frequency Graph-Transformer Networks for Subject-Independent EEG Classification of Neurodegenerative Disorders