Journal of Numerical Simulations in Physics and Mathematics | Volume 2, Issue 1: 1-8, 2026 | DOI: 10.62762/JNSPM.2025.161987
Abstract
Previous research has focused on formulating cancer treatment strategies within a single-drug framework, which clearly fails to effectively address the practical needs of combination drug therapy in clinical settings. Therefore, this study develops a multi-drug cancer treatment model and conducts strategy design and simulation investigations under hypothetical patient-specific parameters for dual-drug regimens. Based on the previously proposed adaptive threshold strategy and several novel strategies integrating threshold-based and sequential administration patterns, and conducted a parameter search and optimization of upper/lower thresholds was performed to explore the performance improvemen... More >
Graphical Abstract