An Intelligent and Secure Application for Early Detection of Eye Disease
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Abstract
This paper presents a deep learning-based intelligent web application for the early detection of eye diseases using retinal fundus images. The dataset used in this study consists of 4,216 retinal fundus images collected from Kaggle, representing multiple eye disease categories. Multiple deep learning architectures, including CNN, DenseNet, InceptionV3, and ResNet, were evaluated and compared with a proposed modified MobileNetV2 architecture. The proposed architecture enhances the baseline MobileNetV2 by optimizing feature extraction and classification layers for improved performance in multi-class eye disease detection. Experimental results show that the proposed model achieved an overall classification accuracy of 88%, outperforming other evaluated models, including CNN (85.87%), DenseNet (87.19%), InceptionV3 (82.88%), and ResNet (50.67%), while maintaining low computational complexity. To improve transparency and interpretability of the deep learning model, Grad-CAM was integrated to visualize the discriminative regions of fundus images influencing the model’s predictions. The optimized model was deployed within a smart web application using a Flask backend and Streamlit frontend, enabling real-time disease prediction and visual explanation of results. The proposed system demonstrates the effectiveness of lightweight deep learning architectures combined with explainable AI techniques for accessible and reliable web-based ophthalmic diagnostic support systems. The optimized lightweight model was deployed as a mobile-friendly web application using Flask and Streamlit, enabling real-time inference on resource-constrained mobile devices and supporting wireless remote access for ophthalmic screening in underserved areas.
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References
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Cite This Article
TY - JOUR AU - Haque, A. K. M. Fazlul AU - Hridoy, Raihan Ahmed AU - Hossain, Meherab AU - Hasan, Nazia AU - Hridoy, Afzal Hossain AU - Akter, Taslima PY - 2026 DA - 2026/04/09 TI - An Intelligent and Secure Application for Early Detection of Eye Disease JO - ICCK Transactions on Mobile and Wireless Intelligence T2 - ICCK Transactions on Mobile and Wireless Intelligence JF - ICCK Transactions on Mobile and Wireless Intelligence VL - 2 IS - 1 SP - 44 EP - 55 DO - 10.62762/TMWI.2026.590606 UR - https://www.icck.org/article/abs/TMWI.2026.590606 KW - eye disease detection KW - mobile intelligence KW - convolutional neural network KW - modified mobileNet KW - deep learning models KW - medical image analysis KW - predictive analytics KW - grad-cam AB - This paper presents a deep learning-based intelligent web application for the early detection of eye diseases using retinal fundus images. The dataset used in this study consists of 4,216 retinal fundus images collected from Kaggle, representing multiple eye disease categories. Multiple deep learning architectures, including CNN, DenseNet, InceptionV3, and ResNet, were evaluated and compared with a proposed modified MobileNetV2 architecture. The proposed architecture enhances the baseline MobileNetV2 by optimizing feature extraction and classification layers for improved performance in multi-class eye disease detection. Experimental results show that the proposed model achieved an overall classification accuracy of 88%, outperforming other evaluated models, including CNN (85.87%), DenseNet (87.19%), InceptionV3 (82.88%), and ResNet (50.67%), while maintaining low computational complexity. To improve transparency and interpretability of the deep learning model, Grad-CAM was integrated to visualize the discriminative regions of fundus images influencing the model’s predictions. The optimized model was deployed within a smart web application using a Flask backend and Streamlit frontend, enabling real-time disease prediction and visual explanation of results. The proposed system demonstrates the effectiveness of lightweight deep learning architectures combined with explainable AI techniques for accessible and reliable web-based ophthalmic diagnostic support systems. The optimized lightweight model was deployed as a mobile-friendly web application using Flask and Streamlit, enabling real-time inference on resource-constrained mobile devices and supporting wireless remote access for ophthalmic screening in underserved areas. SN - 3069-0692 PB - Institute of Central Computation and Knowledge LA - English ER -
@article{Haque2026An,
author = {A. K. M. Fazlul Haque and Raihan Ahmed Hridoy and Meherab Hossain and Nazia Hasan and Afzal Hossain Hridoy and Taslima Akter},
title = {An Intelligent and Secure Application for Early Detection of Eye Disease},
journal = {ICCK Transactions on Mobile and Wireless Intelligence},
year = {2026},
volume = {2},
number = {1},
pages = {44-55},
doi = {10.62762/TMWI.2026.590606},
url = {https://www.icck.org/article/abs/TMWI.2026.590606},
abstract = {This paper presents a deep learning-based intelligent web application for the early detection of eye diseases using retinal fundus images. The dataset used in this study consists of 4,216 retinal fundus images collected from Kaggle, representing multiple eye disease categories. Multiple deep learning architectures, including CNN, DenseNet, InceptionV3, and ResNet, were evaluated and compared with a proposed modified MobileNetV2 architecture. The proposed architecture enhances the baseline MobileNetV2 by optimizing feature extraction and classification layers for improved performance in multi-class eye disease detection. Experimental results show that the proposed model achieved an overall classification accuracy of 88\%, outperforming other evaluated models, including CNN (85.87\%), DenseNet (87.19\%), InceptionV3 (82.88\%), and ResNet (50.67\%), while maintaining low computational complexity. To improve transparency and interpretability of the deep learning model, Grad-CAM was integrated to visualize the discriminative regions of fundus images influencing the model’s predictions. The optimized model was deployed within a smart web application using a Flask backend and Streamlit frontend, enabling real-time disease prediction and visual explanation of results. The proposed system demonstrates the effectiveness of lightweight deep learning architectures combined with explainable AI techniques for accessible and reliable web-based ophthalmic diagnostic support systems. The optimized lightweight model was deployed as a mobile-friendly web application using Flask and Streamlit, enabling real-time inference on resource-constrained mobile devices and supporting wireless remote access for ophthalmic screening in underserved areas.},
keywords = {eye disease detection, mobile intelligence, convolutional neural network, modified mobileNet, deep learning models, medical image analysis, predictive analytics, grad-cam},
issn = {3069-0692},
publisher = {Institute of Central Computation and Knowledge}
}
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