Procollagen-lysine, 2-oxoglutarate 5-dioxygenases (PLODs) catalyze lysine hydroxylation, promoting collagen crosslinking and extracellular matrix stability, and are implicated in tumor aggressiveness. However, their expression and prognostic value in breast cancer (BC) remain unclear. We explored PLOD1-3 expression in BC using ONCOMINE, TIMER, CCLE, cBioPortal, UALCAN, GEPIA, and HPA. Prognostic associations were assessed via Kaplan-Meier Plotter, with enrichment analysis by clusterProfiler. A competing endogenous RNA (ceRNA) network was constructed using TCGA data, and immune infiltration analyzed by TIMER and CIBERSORT. PLOD1-3 were upregulated in BC versus normal tissues at both transcrip... More >