Agricultural Science and Food Processing
ISSN: 3066-1579 (Online) | ISSN: 3066-1560 (Print)
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TY - JOUR AU - Guo, Bin PY - 2026 DA - 2026/01/27 TI - Structural Gatekeepers of Photosynthesis: A Critical Review of CYN38 Dimerization in Chlamydomonas Photosystem II Repair JO - Agricultural Science and Food Processing T2 - Agricultural Science and Food Processing JF - Agricultural Science and Food Processing VL - 3 IS - 1 SP - 1 EP - 5 DO - 10.62762/ASFP.2025.415498 UR - https://www.icck.org/article/abs/ASFP.2025.415498 KW - photosystem II repair KW - CYN38 KW - dimerization KW - chlamydomonas AB - Photosystem II (PSII) repair is a fundamental physiological process governing the resilience of photosynthetic organisms against high light (HL) stress. A recent study by Yao et al. (2025) provides significant mechanistic insights into this process within the model green alga Chlamydomonas reinhardtii. The authors characterize the lumenal immunophilin CYN38, a homolog of the Arabidopsis CYP38, identifying it as a critical auxiliary protein for the biogenesis and stabilization of PSII. Through the characterization of a unique insertion mutant, cyn38, which produces a C-terminally extended protein, the study elucidates that homodimerization of CYN38—mediated by its C-terminus—is a prerequisite for its association with PSII core subunits. This review analyzes the authors' findings regarding the dominant-negative nature of the mutant protein, the evolutionary conservation of immunophilin functions without enzymatic activity, and the structural basis of the PSII repair cycle. We conclude that this study offers a pivotal advancement in understanding the molecular "chaperoning" required for maintaining photosynthetic efficiency under stress. SN - 3066-1579 PB - Institute of Central Computation and Knowledge LA - English ER -
@article{Guo2026Structural,
author = {Bin Guo},
title = {Structural Gatekeepers of Photosynthesis: A Critical Review of CYN38 Dimerization in Chlamydomonas Photosystem II Repair},
journal = {Agricultural Science and Food Processing},
year = {2026},
volume = {3},
number = {1},
pages = {1-5},
doi = {10.62762/ASFP.2025.415498},
url = {https://www.icck.org/article/abs/ASFP.2025.415498},
abstract = {Photosystem II (PSII) repair is a fundamental physiological process governing the resilience of photosynthetic organisms against high light (HL) stress. A recent study by Yao et al. (2025) provides significant mechanistic insights into this process within the model green alga Chlamydomonas reinhardtii. The authors characterize the lumenal immunophilin CYN38, a homolog of the Arabidopsis CYP38, identifying it as a critical auxiliary protein for the biogenesis and stabilization of PSII. Through the characterization of a unique insertion mutant, cyn38, which produces a C-terminally extended protein, the study elucidates that homodimerization of CYN38—mediated by its C-terminus—is a prerequisite for its association with PSII core subunits. This review analyzes the authors' findings regarding the dominant-negative nature of the mutant protein, the evolutionary conservation of immunophilin functions without enzymatic activity, and the structural basis of the PSII repair cycle. We conclude that this study offers a pivotal advancement in understanding the molecular "chaperoning" required for maintaining photosynthetic efficiency under stress.},
keywords = {photosystem II repair, CYN38, dimerization, chlamydomonas},
issn = {3066-1579},
publisher = {Institute of Central Computation and Knowledge}
}
Copyright © 2026 by the Author(s). Published by Institute of Central Computation and Knowledge. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. 
Agricultural Science and Food Processing
ISSN: 3066-1579 (Online) | ISSN: 3066-1560 (Print)
Email: [email protected]
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