A Comparative Analysis of Various Transfer Learning-Based Deep Learning Frameworks Using Brain Tumor MRI
Article Information
Abstract
Brain tumors are a critical and challenging health issue worldwide, and they often reduce patient survival if they are not identified at an early stage. This study presents an automatic approach to identify and classify brain tumor magnetic resonance imaging (MRI) scans using several pre-trained deep learning frameworks and compares their relative performance. Four popular frameworks, namely VGG16, Xception, ResNet50, and MobileNetV1, were fine-tuned with a transfer learning technique on 2870 brain tumor MRI training images to predict four classes (glioma, meningioma, pituitary tumor, and no tumor). A quantitative comparison among all applied frameworks was performed using accuracy, precision, recall, and F1-score. On the held-out test set, VGG16 achieved the highest accuracy (70.1%), followed by Xception (63.7%), MobileNetV1 (53.3%), and ResNet50 (50.8%). The results indicate that VGG16 and Xception outperform the other two frameworks under the same transfer learning setting, while all models show low recall for the glioma class. The study provides a baseline comparison of pre-trained frameworks for brain tumor MRI classification and outlines directions for future research.
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References
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Cite This Article
TY - JOUR AU - Agarwal, Sunil Kumar AU - Gupta, Yogesh Kumar PY - 2026 DA - 2026/10/19 TI - A Comparative Analysis of Various Transfer Learning-Based Deep Learning Frameworks Using Brain Tumor MRI JO - ICCK Transactions on Machine Intelligence T2 - ICCK Transactions on Machine Intelligence JF - ICCK Transactions on Machine Intelligence VL - 2 IS - 4 SP - 200 EP - 212 DO - 10.62762/TMI.2025.919091 UR - https://www.icck.org/article/abs/TMI.2025.919091 KW - Brain tumor MRI classification KW - transfer learning KW - pre-trained model KW - VGG16 KW - Xception KW - ResNet50 KW - MobileNetV1 AB - Brain tumors are a critical and challenging health issue worldwide, and they often reduce patient survival if they are not identified at an early stage. This study presents an automatic approach to identify and classify brain tumor magnetic resonance imaging (MRI) scans using several pre-trained deep learning frameworks and compares their relative performance. Four popular frameworks, namely VGG16, Xception, ResNet50, and MobileNetV1, were fine-tuned with a transfer learning technique on 2870 brain tumor MRI training images to predict four classes (glioma, meningioma, pituitary tumor, and no tumor). A quantitative comparison among all applied frameworks was performed using accuracy, precision, recall, and F1-score. On the held-out test set, VGG16 achieved the highest accuracy (70.1%), followed by Xception (63.7%), MobileNetV1 (53.3%), and ResNet50 (50.8%). The results indicate that VGG16 and Xception outperform the other two frameworks under the same transfer learning setting, while all models show low recall for the glioma class. The study provides a baseline comparison of pre-trained frameworks for brain tumor MRI classification and outlines directions for future research. SN - 3068-7403 PB - Institute of Central Computation and Knowledge LA - English ER -
@article{Agarwal2026A,
author = {Sunil Kumar Agarwal and Yogesh Kumar Gupta},
title = {A Comparative Analysis of Various Transfer Learning-Based Deep Learning Frameworks Using Brain Tumor MRI},
journal = {ICCK Transactions on Machine Intelligence},
year = {2026},
volume = {2},
number = {4},
pages = {200-212},
doi = {10.62762/TMI.2025.919091},
url = {https://www.icck.org/article/abs/TMI.2025.919091},
abstract = {Brain tumors are a critical and challenging health issue worldwide, and they often reduce patient survival if they are not identified at an early stage. This study presents an automatic approach to identify and classify brain tumor magnetic resonance imaging (MRI) scans using several pre-trained deep learning frameworks and compares their relative performance. Four popular frameworks, namely VGG16, Xception, ResNet50, and MobileNetV1, were fine-tuned with a transfer learning technique on 2870 brain tumor MRI training images to predict four classes (glioma, meningioma, pituitary tumor, and no tumor). A quantitative comparison among all applied frameworks was performed using accuracy, precision, recall, and F1-score. On the held-out test set, VGG16 achieved the highest accuracy (70.1\%), followed by Xception (63.7\%), MobileNetV1 (53.3\%), and ResNet50 (50.8\%). The results indicate that VGG16 and Xception outperform the other two frameworks under the same transfer learning setting, while all models show low recall for the glioma class. The study provides a baseline comparison of pre-trained frameworks for brain tumor MRI classification and outlines directions for future research.},
keywords = {Brain tumor MRI classification, transfer learning, pre-trained model, VGG16, Xception, ResNet50, MobileNetV1},
issn = {3068-7403},
publisher = {Institute of Central Computation and Knowledge}
}
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