Volume 2, Issue 1, ICCK Journal of Software Engineering
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ICCK Journal of Software Engineering, Volume 2, Issue 1, 2026: 11-29

Open Access | Research Article | 30 January 2026
FusedCNN-LSTM: A Software-Oriented Multimodal Deep Learning Framework for Intelligent Hypertension Risk Prediction
1 Department of Computer Science, COMSATS University Islamabad, Sahiwal 57000, Pakistan
2 Department of Software Engineering, Riphah International University, Islamabad 44000, Pakistan
* Corresponding Authors: Aamir Ali, [email protected] ; Misbah Ali, [email protected]
ARK: ark:/57805/jse.2025.995217
Received: 04 August 2025, Accepted: 17 November 2025, Published: 30 January 2026  
Abstract
Hypertension, a life-threatening global health challenge, requires early detection to prevent severe cardiovascular complications. Fundus imaging reveals microvascular alterations, yet conventional diagnosis often misses subtle early changes. This study introduces a multimodal deep learning framework that integrates clinical data, fundus images, and demographic features to improve hypertension prediction. Unlike single-modality approaches, our method captures complementary risk factors from both structured and unstructured data. We evaluate machine learning and deep learning models on clinical data, confirming DL's superior accuracy. For fundus images alone, a CNN achieves 74.44% accuracy, highlighting the limitations of unimodal image analysis. To overcome this, we propose a fused CNN-LSTM architecture that models both spatial biomarkers and temporal clinical trends. The framework achieves robust performance, with an overall accuracy of 98% and minimal variation across datasets. Implemented in TensorFlow/Keras, the system adopts a modular, software-oriented design, ensuring flexibility, ease of maintenance, and seamless integration into clinical workflows. This holistic approach enables timely intervention, improves patient outcomes, and reduces healthcare burdens.

Graphical Abstract
FusedCNN-LSTM: A Software-Oriented Multimodal Deep Learning Framework for Intelligent Hypertension Risk Prediction

Keywords
convolutional neural network
long short-term memory
hypertension
machine learning
deep learning

Data Availability Statement
Data will be made available on request.

Funding
This work was supported without any funding.

Conflicts of Interest
The authors declare no conflicts of interest.

AI Use Statement
The authors declare that no generative AI was used in the preparation of this manuscript.

Ethical Approval and Consent to Participate
Not applicable.

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Cite This Article
APA Style
Farooq, W., Ali, A., Fatima, H. M., Rafiq, W., Zainab, N. E., & Ali, M. (2026). FusedCNN-LSTM: A Software-Oriented Multimodal Deep Learning Framework for Intelligent Hypertension Risk Prediction. ICCK Journal of Software Engineering, 2(1), 11–29. https://doi.org/10.62762/JSE.2025.995217
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TY  - JOUR
AU  - Farooq, Wajiha
AU  - Ali, Aamir
AU  - Fatima, Hafza Mehreen
AU  - Rafiq, Wasif
AU  - Zainab, Noor E
AU  - Ali, Misbah
PY  - 2026
DA  - 2026/01/30
TI  - FusedCNN-LSTM: A Software-Oriented Multimodal Deep Learning Framework for Intelligent Hypertension Risk Prediction
JO  - ICCK Journal of Software Engineering
T2  - ICCK Journal of Software Engineering
JF  - ICCK Journal of Software Engineering
VL  - 2
IS  - 1
SP  - 11
EP  - 29
DO  - 10.62762/JSE.2025.995217
UR  - https://www.icck.org/article/abs/JSE.2025.995217
KW  - convolutional neural network
KW  - long short-term memory
KW  - hypertension
KW  - machine learning
KW  - deep learning
AB  - Hypertension, a life-threatening global health challenge, requires early detection to prevent severe cardiovascular complications. Fundus imaging reveals microvascular alterations, yet conventional diagnosis often misses subtle early changes. This study introduces a multimodal deep learning framework that integrates clinical data, fundus images, and demographic features to improve hypertension prediction. Unlike single-modality approaches, our method captures complementary risk factors from both structured and unstructured data. We evaluate machine learning and deep learning models on clinical data, confirming DL's superior accuracy. For fundus images alone, a CNN achieves 74.44% accuracy, highlighting the limitations of unimodal image analysis. To overcome this, we propose a fused CNN-LSTM architecture that models both spatial biomarkers and temporal clinical trends. The framework achieves robust performance, with an overall accuracy of 98% and minimal variation across datasets. Implemented in TensorFlow/Keras, the system adopts a modular, software-oriented design, ensuring flexibility, ease of maintenance, and seamless integration into clinical workflows. This holistic approach enables timely intervention, improves patient outcomes, and reduces healthcare burdens.
SN  - 3069-1834
PB  - Institute of Central Computation and Knowledge
LA  - English
ER  - 
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@article{Farooq2026FusedCNNLS,
  author = {Wajiha Farooq and Aamir Ali and Hafza Mehreen Fatima and Wasif Rafiq and Noor E Zainab and Misbah Ali},
  title = {FusedCNN-LSTM: A Software-Oriented Multimodal Deep Learning Framework for Intelligent Hypertension Risk Prediction},
  journal = {ICCK Journal of Software Engineering},
  year = {2026},
  volume = {2},
  number = {1},
  pages = {11-29},
  doi = {10.62762/JSE.2025.995217},
  url = {https://www.icck.org/article/abs/JSE.2025.995217},
  abstract = {Hypertension, a life-threatening global health challenge, requires early detection to prevent severe cardiovascular complications. Fundus imaging reveals microvascular alterations, yet conventional diagnosis often misses subtle early changes. This study introduces a multimodal deep learning framework that integrates clinical data, fundus images, and demographic features to improve hypertension prediction. Unlike single-modality approaches, our method captures complementary risk factors from both structured and unstructured data. We evaluate machine learning and deep learning models on clinical data, confirming DL's superior accuracy. For fundus images alone, a CNN achieves 74.44\% accuracy, highlighting the limitations of unimodal image analysis. To overcome this, we propose a fused CNN-LSTM architecture that models both spatial biomarkers and temporal clinical trends. The framework achieves robust performance, with an overall accuracy of 98\% and minimal variation across datasets. Implemented in TensorFlow/Keras, the system adopts a modular, software-oriented design, ensuring flexibility, ease of maintenance, and seamless integration into clinical workflows. This holistic approach enables timely intervention, improves patient outcomes, and reduces healthcare burdens.},
  keywords = {convolutional neural network, long short-term memory, hypertension, machine learning, deep learning},
  issn = {3069-1834},
  publisher = {Institute of Central Computation and Knowledge}
}

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CC BY Copyright © 2026 by the Author(s). Published by Institute of Central Computation and Knowledge. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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